Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury
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چکیده
منابع مشابه
Potential therapeutic effect of pomegranate seed oil on ovarian ischemia/reperfusion injury in rats
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Ischemia/reperfusion injury is a reaction occurring after successful treatment of an acute myocardial infarction or in the setting of solid organ transplantation. After successful reperfusion of a previously occluded vessel or a transplanted organ, an additional loss of otherwise vital cells may occur, the so-called lethal ischemia-reperfusion injury. This lethal reperfusion injury is based on ...
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Annexin A1 (AnxA1) is an endogenous protein that modulates anti-inflammatory processes, and its therapeutic potential has been reported in a range of inflammatory diseases. The effect of AnxA1 on ischemia-reperfusion (IR)-induced lung injury has not been examined. In this study, isolated, perfused rat lungs were subjected to IR lung injury induced by ischemia for 40 min, followed by reperfusion...
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Leukocyte rolling has been postulated to be mandatory for subsequent leukocyte adhesion and tissue injury observed during ischemia/reperfusion. The objective of this study was to systematically assess this hypothesis at the microvascular level by examining the effects of various concentrations of a selectin-binding carbohydrate (fucoidin) on the increased rolling and adhesion of leukocytes in p...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2018
ISSN: 1422-0067
DOI: 10.3390/ijms19041211